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(For small-molecule drugs like semaglutide, at least seven years must have passed from its FDA approval date to be eligible for selection, and for drugs with multiple FDA approvals, CMS will use the earliest approval date to make this determination.) If that happens, a negotiated Medicare price would be available beginning in 2027

164 Notably, larger doses or longer durations of GLP-1RA therapy have been associated with an increased risk of cholelithiasis, 165 a primary risk factor for AP

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Antioxidants are essential to maintaining a healthy immune system, detoxifying your body, and removing free radicals that can contribute to cellular damage