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These tools supported remote, standardized assessment of clinical benefit, particularly in decentralized trial settings

But when exposure to triggers becomes chronic, and your TLRs are continuously activated, it can cause your mast cells to become highly sensitive and over-reactive.13,14 In mast cell activation syndrome, or MCAS, chronic TLR activation creates hypersensitive mast cells that get stuck in overproduction mode setting off an inflammatory response that can spread throughout your body

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Statistical analysis Statistical analyses were performed utilizing IBM SPSS Statistics, version 28 (IBM Corp., Armonk, NY, USA)