Because its effects on fetal and infant development are unknown, its best to avoid use unless prescribed and monitored by a qualified healthcare provider
Siavashpour A, Khalvati B, Azarpira N, Mohammadi H, Niknahad H, Heidari R
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Under continuous stimulation of IGF-1, IGF-1R/MAPK/PI3K signaling is activated, leading to resistance to estrogen tamoxifen and fluvestrant