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Common side effects and their typical resolution timeline The overarching theme: most gastrointestinal side effects are transient and self-limiting

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This exopeptidase selectively cleaves N-terminal dipeptides from a variety of substrates, including cytokines, growth factors, neuropeptides, and the incretin hormones

The net effect is therefore best treated as an empirical question, not a settled mechanismconsistent with the comparative observational findings summarised below