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26: 56976 Radack K, Wyderski RJ

Rather than a direct effect on platelet activation, thrombus formation, or atherosclerotic plaque stability, this benefit is postulated to result from a reduction in preload with a resultant reduction in myocardial wall tension, myocardial oxygen demands, and a consequential reduction in myocardial ischemia [8]

For some individuals with higher BMIs or obesity-related health conditions, injectable medications may be one part of a broader strategy

Patients in clinical trials reported average weight reductions ranging from 15% to 22% of baseline body weight over 12 to 52 weeks, depending on dosage and adherence