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Stem Cell Mobilisation, Scar Reduction & Multi-System Repair (PubMed, 2012) A comprehensive review of TB4s biological properties confirmed it is released by platelets, macrophages, and multiple cell types following injury, where it protects tissues from further damage while reducing apoptosis, inflammation, and microbial growth

SCFAs produced by probiotic fermentation, bind to G protein-coupled receptors GPR41 and GPR43 on immune cells, attenuating NF-B and MAPK signaling pathways in neutrophils and suppressing oxidative burst and cytokine release (146, 149)

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