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Oral tranexamic acid was originally FDA approved to treat bleeding disorders

These effects help patients: Lower blood sugar Lose weight Reduce cardiovascular risk Drugs in this class include: Ozempic (semaglutide, injectable) Rybelsus (oral semaglutide) Wegovy (semaglutide for weight loss) Trulicity (dulaglutide) Victoza (liraglutide) Ozempic and Rybelsus, in particular, have skyrocketed in popularity not only for diabetes management but also for off-label weight loss

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Finally, T5 , analogous to T1 where hydroxyl groups are substituted by methoxy groups, results in an IC 50 = 40.02 M, suggesting that hydrogen bonds (provided by the hydroxyl groups) are more favorable than the hydrophobic interactions (supported by the methoxy groups) in mushroom tyrosinase inhibition (Supplementary Fig