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Cycle Guidelines CagriSema Cycle Length Reference Approach Trial-mirroring cycle Duration 68 weeks Off Period Per clinician guidance Best For Matching REDEFINE 1 / REDEFINE 2 clinical trials

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In REDEFINE 2, 73.5% of CagriSema participants reached HbA1c 6.5% versus 15.9% on placebo (treatment-policy estimand)