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Dietitians play an essential role in supporting clients using GLP-1s, helping them make necessary dietary adjustments to maximize the medication's effectiveness, promote satiety, and ensure balanced nutrient intake

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We identified 55 distinct disease-causing variants in SERPING1 gene, including 23 missense, 12 nonsense, 9 frameshift, 2 in-frame deletions, 3 splicing defects, 1 promoter substitution, and 5 large insertions/deletions

The effect is broad rather than targeted