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While repair and regeneration compose a topic in and of itself and worthy of another post, the point is that it would be desirable to seek new therapeutic agents that may interrupt the amplified oxidative/nitrosative cycle before necrosis is established in surviving hepatocytes so that they may recover, including through removal or repair of damaged mitochondria

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The use of TOUJEO for this indication is supported by evidence from an adequate and well-controlled study in 463 pediatric patients 6 to 17 years of age with type 1 diabetes mellitus [see Clinical Studies (14.2)] and from studies in adults with diabetes mellitus [see Clinical Pharmacology (12.3), Clinical Studies (14.3)]