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the clinical relevance of this finding in humans is unknown, and in UK and EU prescribing information this is noted as a precaution rather than a formal contraindication but individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) should discuss this with their doctor

Methyl B12 is the most promising treatment for patients with severe neurological symptoms, bypassing several steps in the absorption cycle and helping to relieve or completely reverse symptoms