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Enzymatic cleavage compromises membrane integrity, facilitating cargo release [91]
To identify POMC neurons and GLP-1 receptor-positive neurons, POMC humanized Renilla green fluorescent protein (hrGFP) (The Jackson Laboratory, 006421) and GLP-1 receptor cre::tdTomato (The Jackson Laboratory, 029283) mice were used
These results offer novel insights around the multiple mechanisms that drive NASH and demonstrate the potential of combination approaches for patients in significant need of a treatment option for this condition, said Naim Alkhouri, director of the Fatty Liver Program, chief of Transplant Hepatology, Arizona Liver Health, Chandler
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