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This review synthesizes the mechanistic rationale, pre-clinical evidence, and clinical data to date, highlighting the potential utility and safety considerations of glucagon-like peptide-1 receptor agonists in IBD and emphasizes the need for robust prospective trials to ascertain their safety and efficacy in this patient population

Retatrutide also known as Reta or LY3437943 is an experimental synthetic peptide currently studied in clinical trials for the management of obesity and diabetes

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