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Pyruvate, generated from glycolysis, exerts differential inhibitory actions on the various PDK

This pathway increases NO production, essential for endothelial proliferation, vessel dilation, and new capillary formation, which may be particularly beneficial in ischemic or hypovascular musculoskeletal tissues [20, 24, 26, 39, 41]

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( B ) Transgenic male and female mice treated with GHK-Cu also exhibited lower optical stain density in positively stained tissues within the hippocampus in comparison to saline-treated counterparts