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, IL-6, MPO activity, and other mediators 1

She is dark, she is fat and she wears specs all the time

PLoS Biol 2018;16, e2004663, doi:10.1371/journal.pbio.2004663

studied 69 patients with IC/PBS (diagnosed based on the 1987 NIH criteria and including both ESSIC types 2 and 3) and 37 controls (with and without non-IC/BPS chronic cystitis) and demonstrated that the presence of mast cells correlated with the level of background lymphoplasmacytic infiltrate, but not with the diagnosis of IC