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Studies have shown that duodenal tissues from Celiac patients exhibit reduced expression of several scavenger receptors, including SR-B2, thrombospondin-1 (TSP-1), and CD61, alongside elevated levels of inflammatory cytokines such as IL-15, IL21, and IFN- (370)

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observed bacterial activation of hepatic Nrf2 via the metabolite 5-methoxyindoleacetic acid, which protected the liver against the harmful effects of acetaminophen or ethanol (71)

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