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This is the stage that the original researchers were targetinga state of enhanced photoprotection

Por accin de la enzima trimetil lisina dioxigenasa (TML-DO, EC 1.14.11.8) se hidroxila la posicin 3 de la TML para formar la 3-hidroxi- N 6 , N 6 -trimetil lisina ( HTML ) en presencia de oxgeno diatmico como agente oxidante, -cetoglutarato como aceptor de electrones, adems de hierro (II) y cido ascrbico como cofactores

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Endothelial dysfunction, dysregulation of ER stress and autophagy pathways, mitochondrial toxicity, calcium imbalance, and several other side effects have also been observed in kidneys, the gut, major arteries, liver, and other organs (Apostolova et al