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The mechanism of medicinal plants is broad, and includes regulation of intestinal microbiota composition and intestinal permeability, increased expression of both mRNA and claudin-1 protein, and anti-inflammatory effects (Chinese tea, hibiscus, liquorice, marshmallow, ginger root, peppermint, plantain, curcumin)

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[7] In other words, by inhibiting this interaction, FOXO4-DRI might enhance the organisms ability to clear these cells without significantly impacting other functions of FOXO4

Krasemann S, Madore C, Cialic R, Raufeld C, Calcagno N, et al