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Abbreviations MPS: Mono nuclear phagocyte system PEG: Polyethylene glycol TTIP: Titanium tetra isopropoxide HRTEM: High-resolution transmission electron microscopy FT-IR: Fourier-transform infrared spectroscopy AOM: Azoxymethane ZOI: Zone of inhibition rGO-TiO2: Phytoreduced graphene oxide-titanium dioxide MRSA: Methicillin-resistant S

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No new safety signals emerged and treatment discontinuation due to adverse events was comparable between the drug and placebo groups