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How Incretin Mimetics Protect the Brain: GLP-1R agonists & GLP-1RGIPR coagonists cross the BBB partially, reaching brainstem/hypothalamus via circumventricular organs (CVOs) or pericyte transport

A study published in the Journal of Clinical Pharmacology highlighted the superior bioavailability of IV-administered substances compared to their oral counterparts, underlining the efficiency of IV drips in delivering glutathione directly to where its needed most

Konturek SJ, Czesnikiewicz-Guzik M