Depending on patient needs and treatment objectives, these therapies could be given topically, orally, or via injections
In terms of pharmacological properties, DON and BPTES show moderate potency, poor metabolic stability, low water solubility, and limited selectivity for GLS, resulting in inferior antitumor efficacy compared to CB-839 (246, 247)
Member of the Latinoamerican Board of Eli Lilly and Sanofi Aventis Member of the National Board of the following laboratories: Novo Nordisk, Novartis, GlaxoSmithKlein Sanofi, Aventis, Boheringer Ingelheim, Bristol Myers, Astra Zeneca Main investigator of Protocols from: Eli Lilly, Novo Nordisk, Novartis, GlaxoSmithKlein, Takeda, PPDF, Pfizer, Merck Sharp Dome, Amgen, Roche, Minimed, Quintiles Speakers of the former laboratories
Drug reaction with eosinophilia and systemic symptoms (DRESS) This is a rare type of drug rash that can be life threatening