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Glutathione: * Protects LDL from oxidation * Reduces vascular inflammation * Supports nitric oxide function * Improves endothelial health * Assists mitochondrial ATP production * Detoxifies lipid peroxidation byproducts Cellular glutathione declines as we age after 20, and is further stressed in APOE4 carriers

To sustain physiological conditions and functions, there is a GSSG to GSH ratio that favors GSH