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Key considerations include: Increased risk of hypoglycemia when used with insulin or sulfonylureas Possible need for INR monitoring if taking warfarin Limited clinically relevant effects on most other oral medications Understanding what's normal during the initial treatment period helps set realistic expectations and identify situations requiring medical attention

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Since GLP-1 medications slow gastric emptying and can cause nausea, some patients report that evening dosing helps them manage these symptoms overnight

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