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The second layer of the gut barrier is composed of a monolayer of intestinal epithelial cells and intercellular tight junction (TJ) proteins, with a scattered distribution of functionally specialized cells (e.g., Paneth, goblet, and enteroendocrine cells) (Ghosh et al., 2021)

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GLP-1 patient trends: demographics and adherence patterns Usage across the population A nationally representative survey conducted by RAND found that 11.8% of Americans have used GLP-1 drugs for weight loss, and about 14% express interest, while 74% say they do not plan to take them