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In a third trial, liraglutide significantly reduced weight by 8 pounds relative to placebo over 10 months in stable patients with bipolar disorder regardless of whether they were taking an antipsychotic (McElroy SL et al, J Clin Psychopharm 2024;44(2):8995)

Firstly, the liver is critical in synthesizing L-carnitine and, if diseased, L-carnitine biosynthesis is reduced which may affect whole body fatty acid metabolism

Metabolites 15 , 208 (2025)

Common GLP-1 side effects include: Nausea Vomiting Diarrhea Constipation Abdominal Pain Hypoglycemia Side effects that are less likely include: Pancreatitis Gallbladder Problems Joint Pain Headaches Upper Respiratory Infections With GLP-1 the effects of long-term use are still not well researched