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Week-by-week dosage comparison Weight loss comparison at matched timepoints *Tirzepatide 24 and 48-week figures estimated from SURMOUNT-1 trajectory data, as primary endpoint was 72 weeks

Adults with a BMI of 27 kg/m or above who also have at least one weight-related condition, such as type 2 diabetes, high blood pressure, or dyslipidaemia

When to reassess If GI symptoms worsen instead of improving over the first 2-3 weeks, if any unusual symptom appears, or if blood glucose readings drop more than expected, pause and consult a qualified clinician

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