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Gressner OA, Lahme B, Siluschek M, Weiskirchen R, Gressner AM (2008)

In animal studies, administration of dexamethasone caused a reduction of GLP-1 secretion from the intestinal L cells [80] and also decreased the circulating levels of this peptide, which led to glucose intolerance and peripheral insulin resistance in rats [81]

To conclude, both AD populations and animal models have been demonstrated to exhibit abnormalities in relevant proteins that regulate mitochondrial biogenesis, mitophagy, and mitochondrial dynamics