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For instance, one study found that growth hormone (GH) secretagogues similar to ipamorelin helped increase lean body mass and decrease fat mass in a group of seniors [11], but it is not known whether ipamorelin offers these benefits

Frataxin-knockout mouse myoblasts, heart, and skin fibroblasts all showed characteristics of ferroptosis, and Nrf2 was downregulated in Friedreichs Ataxia patients and frataxin-knockout mice, while Nrf2 activators EPI-743 or sulforaphane regulated redox imbalances and rescued ferroptosis in frataxin knockout cells

This is possible because these medications act through different mechanisms

doi: 10.1016/j.clinbiochem.2010.02.005 80 RamliNSFMat JunitSLeongNKRazaliN