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As all species involved in this catalytic mechanism (NADPH, FAD, disulfide pairs, and oxidants) are redox active and it was determined that all discerned states were quasi-equilibrium states that include combinations of extents of oxidation and reduction for all redox active species
As we age, glutathione levels tend to decline in various tissues, putting cells at an increased risk of stress-related damage
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TBT has also been reported to be an environmental risk factor for Parkinsons disease, by inhibiting dopamine biosynthesis and enhancing L-DOPA-induced cytotoxicity (Kim et al., 2007)
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