The brain has its own GLP-1 signaling system, which helps guide appetite in ways researchers are still just beginning to unravel
ACC American College of Cardiology, AHA American Heart Association, ESC European Society of Cardiology, ADA American Diabetes Association, GLP-1 RA glucagon-like peptide 1 receptor agonists, T2DM type 2 diabetes mellitus, ASCVD atherosclerotic cardiovascular disease, CV cardiovascular, CVD cardiovascular disease, MACE major adverse cardiovascular event, SGLT2i sodium-glucose co-transporter 2 inhibitors, BMI body mass index, MI myocardial infarction, HFpEF heart failure with preserved ejection fraction a ACC/AHA and ESC utilize class of recommendation (1, 2a, 2b, 3) which highlights the overall benefit of a treatment compared to its risks
Scheerer, P
Both are regenerative actives with strong mechanism evidence