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Quick Summary What it is: A synthetic peptide that activates three receptors at once GLP-1, GIP, and glucagon

In people with T2D, 48% of the participants achieved 10% WL after 26 weeks of treatment with orforglipron 45 mg in a phase 2 trial (Fig

Below is a summary (definitely not exhaustive) for the landscape of weight loss drugs in development (including company name and formulation, dosing and mechanism), showing my estimation of when these could launch and become available for patients

You might remember the old rhyme: Beans, beans, theyre good for your heart. That rhyme hints at fermentation: fiber in beans leads to SCFAs, which help trigger GLP-1