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Soluble VCAM-1 impairs human brain endothelial barrier integrity via integrin -4-transduced outside-in signalling

These analyses are then presented to the Ontario Health Technology Advisory Committee, whose mandate is to examine proposed health technologies in the context of available evidence and existing clinical practice, and to provide advice and recommendations to Ontario health care practitioners, the broader health care system, and the Ontario Ministry of Health and Long-Term Care

Additionally, EPA and DHA are precursors to specialized pro-resolving mediators such as resolvins and protectins, which mediate the resolution of chronic neuroinflammation and tissue repair 37