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These materials will contain FDAs preliminary analysis of the clinical evidence, safety data, and any concerns

You can certainly combine the shots in the same syringe, but I do not recommend it (unless you are an expert), because if you get an air bubble in the syringe, as you extract the liquid from the vial, you will need to slowly return the liquid into the vial and re-extract it again till theres no bubbles

A miscalculated volume produces an incorrect concentration that propagates through every subsequent measurement

First, pull the plunger back to draw in an amount of air equal to the volume of water you're about to withdraw (e.g., 2mL of air)