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all data come from cell cultures and rodents

305 Hence, it can be stated that the co-activator molecules have a critical role in autism spectrum disorder (ASD) and therefore, can be a good therapeutic target for amelioration of ASD and related diseases

Another study on cardiometabolic risk factors in a diabetes case-control study (NCT02588898) and a vitamin-supplementation trial (NCT02586181) found high plasma concentrations of metabolites, including TMAO and choline, correlated with lower cholesterol and plasma phospholipid levels, suggesting TMAO may aid in cholesterol solubilization and macrophage cholesterol (158)