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Immediate allergic reactions are rare in the published literature, but delayed immunological effects have been documented in animals

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This is especially important for people at risk for multiple deficiencies, including those with GI conditions, a history of gastric bypass surgery, impaired kidney function, older adults, and people taking PPIs

Another theory thought to be associated with the development of ASD is the leaky gut hypothesis. This hypothesis posits that increased intestinal permeability in children with ASD may lead to enhanced absorption of agents within the gut lumen, which could contribute to the development of the disorder