Our results indicate that VRK2 phosphorylates COPII component Sec24C and promotes its interaction with SLC7A11, thus facilitating ER-to-Golgi transport and membrane expression of SLC7A11
These include, increased inducible nitric oxide (NO) synthase (iNOS)-derived NO production [39, 40], increased inflammation [30, 39], increased oxidative stress [30, 31, 38], and increased apoptosis and -cell death [39, 40]
Individuals with B12 deficiency may be more susceptible to infections and have a weakened immune response
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