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The combination of a BET inhibitor (+)-JQ-1 and a proteasome inhibitor bortezomib (BTZ) has been shown to decrease GPX4 expression, thereby inducing ferroptosis in TNBC [18]
Gejl, M., Lerche, S., Egefjord, L.,Brock, B., Moller, N., Vang, K., Rodell, A.B., Bibby, B.M., Holst, J.J., Rungby, J., Gjedde, A., (2013) Front Neuroenergetics 5, 2
Welldesigned human trials that test rational combinations and report body composition and hormone changes will be especially valuable for refining natural alternatives to GLP1
Optional vitamin C co-infusion enhances the antioxidant and tyrosinase-inhibition effect
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