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These chemical messengers include: Histamine Prostaglandins Cytokines In someone without MCAS, the amount of these chemical messengers released is just enough to help the body fight off and heal from the infection, allergen, or other threat

Animal findings, human events, and causal conclusions should not be combined into a consumer warning list without context

Furthermore, patients with AP often receive medications (e.g., sedatives, antibiotics, and vasoactive agents) that can influence cytoskeletal organization and mitochondrial function, complicating the clinical applicability of strategies derived from reductionist models

Future research should aim to define the optimal perioperative discontinuation interval for GLP-1-RA users, stratified by symptomatology, and to evaluate the efficacy of preoperative gastric ultrasound in detecting residual gastric content and reducing aspiration risk