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Scientific Reports (2019) 3

Although a number of therapeutic approaches have been used for women with presumed extrapelvic endometriosis, the reported efficacy of ovarian suppression with a GnRH agonist appears to support it as the first line of therapy except in cases of obstruction of the ureter or bowel, which are best treated surgically (38)

This surge in oxidative stress disrupts mitochondrial function and triggers programmed cell death, enabling the selective elimination of metabolically adaptable tumor cells [43, 129]

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