tirzepatide cardiovascular outcomes trial for Heart Failure with Preserved Ejection Fraction and Obesity In patients with cardiometabolic #HFpEF,

Ongoing investigations into telomere and telomerase-related pathways

The following side effects have been reported in subjects taking 3mg liraglutide for weight loss [24]: Nausea (39.3%) Diarrhea (20.9%) Constipation (19.4%) Vomiting (15.7%) Headache (up to 13.6%) Increases in mean resting heart rate (over 10% ) Less common side effects that occur in less than 10% of patients are: Dyspepsia Abdominal pain Gastroesophageal reflux disease Eructation Flatulence Dry mouth Elevated pancreatic enzymes Constipation Gastritis Abdominal discomfort Hypoglycemia Dizziness Hypotension Injection site reactions (pain, bleeding, redness, swelling, or itching) Rare but serious side effects include pancreatitis, gallbladder disease, cholestasis, and allergic reactions

Thrift, A

Polyethylene glycol, an effective osmotic laxative, has been shown to have potential in improving CHE [147]