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3 4 But there are no completed human clinical trials showing it treats any inflammatory disease, and it is not approved for any indication

9 , e002816 (2016)

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It is therefore unsurprising that the LD 50 values for compounds 1 and 2 determined ex vivo have a similar discordance to that seen for PZQ when considering in vivo PK/PD: much like PZQ these compounds are schistosomicidal in vivo at sub LD 50 concentrations