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Acetyl L-carnitine and propionyl L-carnitine administered singly or separately together with sildenafil never showed statistically significant superior activity compared to the group treated with sildenafil alone

The Hostynek and Maibach group at UCSF measured exactly this in 2011: human skin permeation of GHK-Cu as a function of skin layer, with the result that the peptide accumulates in the upper stratum corneum but does not pass through to viable epidermis or dermis in any meaningful quantity 4

Statements Author contributions SB: conceptualization, visualization, and writingoriginal manuscript