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CHE is defined by the presence of neuropsychological/neurophysiological abnormalities, such as deficits in attention, working memory, response inhibition, and visuomotor coordination, in the absence of overt neurological signs, and is detectable only through specialized testing [2,3,4,5,6]

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b) Nachhaltigkeit Whrend der STEP-1-Studienverlngerung [11] wurde nach 68 Wochen ein erheblicher Gewichtsverlust unter Semaglutid beobachtet, aber nach Absetzen des Medikaments trat Gewichtszunahme auf, siehe Abbildung 1

[20] Mechanism of action [edit] Exenatide binds to the intact human glucagon-like peptide-1 receptor (GLP-1R) in a similar way to the human peptide glucagon-like peptide-1 (GLP-1)