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Cigarette smoke induces proinflammatory cytokine release by activation of NF-B and posttranslational modifications of histone deacetylase in macrophages

Although fibrous astrocytes are less frequently associated with classical tripartite synapses, they modulate axonal conduction and participate in axoglial interactions that share functional similarities with tripartite arrangements, thereby supporting neuronal communication and structural integrity

These findings reveal the high degree of molecular heterogeneity underlying genetic obesity and indicate that its clinical manifestations can range from relatively isolated severe metabolic disturbances to complex syndromes accompanied by significant neurodevelopmental defects

doi: 10.1016/j.jad.2020.03.029