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Researchers advise that patients prone to herpetic lesions abstain from arginine excess and consider adding supplemental lysine to their diet, 49 particularly during periods of stress. 47 One of lysines critical immune functions is its inhibition of the enzyme arginase (see Lysines Inhibition of Arginase)

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239 Furthermore, autophagy impairmentconsidered a downstream event of mitochondrial dysfunctionhas been associated with ER stress and disordered lipid metabolism, eventually contributing to the development of AP