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Methods Human tissue acquisition and IRB Normal, de-identified human fetal intestinal tissue was obtained from the University of Washington Laboratory of Developmental Biology and was conducted with approval from the University of Michigan Institutional Review Board (IRB

Treatments with DSIP and DSIP-CBBBP are shown to effectively increase melatonin levels, indicating a stress-mitigating potential, whereas CBBBP treatment alone does not significantly affect melatonin levels, pointing to its limited efficacy in this context

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