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Insulin resistance and elevated insulin levels affect the production of sex hormones, so improving insulin sensitivity can shift hormonal balance, often in a positive direction, particularly for women with PCOS

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10.1111/dom.13761 Summary Keywords anti-inflammatory, atherosclerosis, coronary artery disease, glucagon-like peptide-1, mechanisms Citation Skrobucha A, Pindlowski P, Krajewska N, Grabowski M and Jonik S (2024) Anti-inflammatory effects of glucagon-like peptide-1 (GLP-1) in coronary artery disease: a comprehensive review

These differences can influence the metabolic fate of compounds and the precise recapitulation of chronic human disease progression