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Once people stop taking weight-loss medications, the hunger-curbing effects of the drug are removed but their "food environment," such as ultra-processed foods, remains, and weight tends to return, said Dana Small, a professor at McGill University who holds a Canada Excellence Research Chair in metabolism and the brain

At present, considering the considerable impact of carnitines on the Krebs cycle in the modulation of beta oxidative processes (35), it can be inferred that administration of carnitines probably improved the low circulating carnitine plasma levels that PCOS patients have (34), and that this action permitted better cellular function at every level, from brain (i.e