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In the fasted state, SIRT1 deacetylates PGC1 and increases its activity [46]
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T2-weighted imaging of the early stage implants showed a unique and bright signal that was clearly contrasted with the surrounding muscles
This direction was consistent with the model-derived pattern, indicating that these genes were not only selected by the diagnostic algorithm but also showed disease-associated expression shifts in the transcriptomic cohort
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