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We further characterized these TCEs in vitro and in vivo, showing these constructs achieve tumor killing across multiple tumor cell types with high fM - low pM EC 50 and drive robust cytokine production

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For all downstream uses, cell stocks were resuscitated and cultured in RPMI 1640 (media supplemented with 10% (v/v) FBS and 1% (w/v) penicillin/streptomycin at 37C in a humidified atmosphere containing 5% (v/v) CO 2